Addressing Off-Target Effects: Technological Solutions and Enhanced...

a adăugat un sunet Health

2025-11-21 06:19:04 -

Addressing Off-Target Effects: Technological Solutions and Enhanced Specificity Mechanisms Driving Clinical Safety in Gene Editing

The primary technical and clinical barrier to the widespread application of **gene editing in human patients** remains the challenge of **off-target effects**—unintended genetic changes introduced at sites other than the desired target location. These unwanted edits can potentially lead to unforeseen health issues, including the activation of oncogenes or the disruption of...

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